We recently completed a project that covered mitosis and cancer. We learned about what goes on during the cell cycle, including the 3 stages of interphase, mitosis and cytokinesis. Then we went on to explore the relationship between the cell cycle and cancer. We were briefly introduced to two common tumor suppressor genes (p53 and BRCA1) that when functioning normally, regulate the cell cycle thus working to suppress tumor growth. There is another category of genes that when activated eventually lead to causing cancer. These are called oncogenes.
What I would like my students to do is to do a little research and find out more about either a tumor suppressor gene or an oncogene. Since we have already learned about p53 and BRCA1, I do not want you to research these two. When conducting your research, I want you to look for the following:
- Name of the gene
- Which chromosome it is located on
- What that gene’s normal function is
- When the gene isn’t functioning normally, what happens?
- What type of cancer can a malfunction or activation of this gene cause?
In order to received the 10pts extra credit for this assignment, you need to include all of the above in your post, which should be in paragraph form. You will only get credit if your post is well thought out, free of spelling errors use the spell check!!) and in paragraph format.
I’m looking forward to reading what you have learned about tumor suppressor genes and oncogenes!